TopoGEN成立于1991年，是一家專注于拓撲異構酶研究的生物技術公司。總部位于美國，TopoGEN致力于為藥物開發(fā)和機制研究提供創(chuàng)新的產(chǎn)品和服務，特別是在癌癥化療和抗菌藥物的研發(fā)方面。公司由一批在拓撲異構酶領域擁有豐富經(jīng)驗的科學家創(chuàng)立，旨在幫助研究人員深入理解藥物對DNA的作用機制。
主要產(chǎn)品線及特點
拓撲異構酶試劑盒
提供多種與拓撲異構酶相關的試劑盒，適用于藥物篩選和機制研究。
DNA修復報告細胞系
用于藥物發(fā)現(xiàn)，特別是那些通過影響DNA修復途徑增強腫瘤細胞殺傷效果的藥物。
DNA載體和裂解目標
提供用于DNA相關研究的載體和裂解目標，支持多種實驗需求。
拓撲異構酶抑制劑和抗體
用于研究和臨床診斷，特別是在檢測和研究拓撲異構酶相關疾病方面。
藥物篩選試劑盒
用于識別拓撲異構酶活性藥物，適用于癌癥化療和抗菌應用。
產(chǎn)品優(yōu)勢
TopoGEN的產(chǎn)品以其高質(zhì)量和創(chuàng)新性著稱，所有產(chǎn)品均經(jīng)過科學家的驗證和認證。公司提供靈活高效的內(nèi)部測試程序，能夠在短時間內(nèi)完成項目，并提供詳盡的時間規(guī)劃。此外，TopoGEN與客戶建立合作關系，提供數(shù)據(jù)審查和有價值的輸入，確?？蛻粼谘芯恐蝎@得最佳支持。
熱門產(chǎn)品介紹
Human Topoisomerase II Assay Kit
特點：用于分析拓撲異構酶II活性的藥物篩選。
貨號：TG1001-1。
應用領域：廣泛應用于癌癥研究和藥物開發(fā)。
Topoisomerase I Drug Screening Kit
特點：專門用于篩選影響拓撲異構酶I活性的藥物。
貨號：TG1018-1。
應用領域：適用于抗癌藥物的研發(fā)。
Monoclonal Antibody to Human Topoisomerase II Alpha
特點：高特異性單克隆抗體，用于檢測人類拓撲異構酶IIα。
貨號：TG2010-1。
應用領域：適用于基礎研究和臨床診斷。
公司競爭優(yōu)勢
TopoGEN的競爭優(yōu)勢在于其專業(yè)的研發(fā)團隊和豐富的產(chǎn)品線。公司擁有先進的活細胞測試技術和雙重凝膠分析系統(tǒng)，能夠為客戶提供深入的化合物分析。此外，TopoGEN的合同研究組織（CRO）服務能夠快速響應客戶需求，提供高效的實驗室支持。
客戶人群
TopoGEN的客戶主要包括全球的大學和研究機構、藥物開發(fā)公司、臨床研究機構以及生物技術公司。這些客戶利用TopoGEN的產(chǎn)品進行基礎和應用研究，特別是在癌癥和抗感染藥物的研發(fā)方面。
社會責任與可持續(xù)發(fā)展
TopoGEN積極履行社會責任，致力于可持續(xù)發(fā)展。公司在生產(chǎn)過程中遵循環(huán)保原則，努力減少對環(huán)境的影響，并通過技術創(chuàng)新推動行業(yè)的可持續(xù)發(fā)展。TopoGEN還注重與客戶的合作，確保研究成果的保密性和安全性，以促進科學研究的進步。
熱賣產(chǎn)品
| 貨號 | 品名 | 規(guī)格 | 價格 |
| DR3000 HRHeLa-Sce | HR based Kit in HeLa Requiring I-Sce1 Transfection (50ug DNA) | 50ug | 31600 |
| DR3000 HRHeLa-Sce2 | HR based Kit in HeLa Requiring I-Sce1 Transfection (100ug DNA) | 100ug | 35920 |
| DR3000 HRHeLa-Sce3 | HR based Kit in HeLa Requiring I-Sce1 Transfection (250ug DNA) | 250ug | 44720 |
| DR3000 HRHeLa-CPR | HR based Kit in HeLa Requiring CRISPR Transfection (50ug DNA) | 50ug | 33360 |
| DR3000 HRHeLa-CPR2 | HR based Kit in HeLa Requiring CRISPR Transfection (100ug DNA) | 100ug | 37680 |
| DR3000 HRHeLa-CPR3 | HR based Kit in HeLa Requiring CRISPR Transfection (250ug DNA) | 250ug | 46320 |
| DR3000 HRCN1.4-Sce | HR based Kit in Mouse Neuronal Cells Requiring I-Sce1 Transfection (50ug DNA) | 50ug | 38640 |
| DR3000 HRCN1.4-Sce2 | HR based Kit in Mouse Neuronal Cells Requiring I-Sce1 Transfection (100ug DNA) | 100ug | 42960 |
| DR3000 HRCN1.4-Sce3 | HR based Kit in Mouse Neuronal Cells Requiring I-Sce1 Transfection (250ug DNA) | 250ug | 51760 |
| DR3000 HRSH-Sce | HR in human Neuroblastoma Cells req. I-Sce1 Transfection (50ug DNA) | 50ug | 38640 |
| DR3000 HRSH-Sce2 | HR in human Neuroblastoma Cells req. I-Sce1 Transfection (100ug DNA) | 100ug | 42960 |
| DR3000 HRSH-Sce3 | HR in human Neuroblastoma Cells req. I-Sce1 Transfection (250ug DNA) | 250ug | 51760 |
| DR3000 HR3T3-Sce | HR based Kit in MOUSE 3T3 Cells Requiring I-Sce1 Transfection (50ug DNA) | 50ug | 31600 |
| DR3000 HR3T3-Sce2 | HR based Kit in MOUSE 3T3 Cells Requiring I-Sce1 Transfection (100ug DNA) | 100ug | 35920 |
| DR3000 HR3T3-Sce3 | HR based Kit in MOUSE 3T3 Cells Requiring I-Sce1 Transfection (250ug DNA) | 250ug | 44720 |
| DR3000 Custom-Sce | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) Includes HRHeLa cell line control (50ug DNA) | 50ug | 38640 |
| DR3000 Custom-Sce2 | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) Includes HRHeLa cell line control (100ug DNA) | 100ug | 42960 |
| DR3000 Custom-Sce3 | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) Includes HRHeLa cell line control (250ug DNA) | 250ug | 51760 |
| DR3000A Custom-Sce | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) No HRHeLa cell line control (50ug DNA) | 50ug | 33360 |
| DR3000A Custom-Sce2 | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) No HRHeLa cell line control (100ug DNA) | 100ug | 37680 |
| DR3000A Custom-Sce3 | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) No HRHeLa cell line control (250ug DNA) | 250ug | 46320 |
| DR5001 HNHela-Sce | NHEJ Based HeLa Requires I-Sce1 Transfection (50ug DNA) | 50ug | 31600 |
| DR5001 HNHela-Sce2 | NHEJ Based HeLa Requires I-Sce1 Transfection (100ug DNA) | 100ug | 35920 |
| DR5001 HNHela-Sce3 | NHEJ Based HeLa Requires I-Sce1 Transfection (250ug DNA) | 250ug | 44720 |
| DR5000 HNSH-Sce | NHEJ Based in Human Neuroblastoma Line requires I-Sce1 transfection (50ug DNA) | 50ug | 38640 |
| DR5000 HNSH-Sce2 | NHEJ Based in Human Neuroblastoma Line requires I-Sce1 transfection (100ug DNA) | 100ug | 42960 |
| DR5000 HNSH-Sce3 | NHEJ Based in Human Neuroblastoma Line requires I-Sce1 transfection (250ug DNA) | 250ug | 51760 |
| DR5000 HN3T3-Sce | NHEJ Based Mouse 3T3 cells Requires I-Sce1 Transfection (50ug DNA) | 50ug | 31600 |
| DR5000 HN3T3-Sce2 | NHEJ Based Mouse 3T3 cells Requires I-Sce1 Transfection (100ug DNA) | 100ug | 35920 |
| DR5000 HN3T3-Sce3 | NHEJ Based Mouse 3T3 cells Requires I-Sce1 Transfection (250ug DNA) | 250ug | 44720 |
| DR5000 Custom-Sce | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) Includes iHNHeLa cell line control (50ug DNA) | 50ug | 43920 |
| DR5000 Custom-Sce2 | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) Includes iHNHeLa cell line control (100ug DNA) | 100ug | 48240 |
| DR5000 Custom-Sce3 | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) Includes iHNHeLa cell line control (250ug DNA) | 250ug | 57040 |
| DR5000A Custom-Sce | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) NO iHNHeLa cell line control (50ug DNA) | 50ug | 33360 |
| DR5000A Custom-Sce2 | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) NO iHNHeLa cell line control (100ug DNA) | 100ug | 37680 |
| DR5000A Custom-Sce3 | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) NO iHNHeLa cell line control (250ug DNA) | 250ug | 46320 |
| DR3050-1 | HR Pooled Cell analysis: 50ug DR-HRGFP, 50ug pSce1, 25ug e-GFP | kit | 14320 |
| DR3050-2 | HeLa Cell RepHR Pooled Cell analysis: 250ug DR-HRGFP, 250ug pSce1, 25ug e-GFP | kit | 54320 |
| DR3050-3 | HR Pooled Cell analysis: 500ug DR-HRGFP, 500ug pSce1, 25ug e-GFP | kit | 79920 |
| DR3050-4 | HR Pooled Cell analysis: 1000ug DR-HRGFP, 1000ug pSce1, 25ug e-GFP | kit | 95920 |
| DRT5050-1 | Detailed protocols with 50ug of cNHEJ plasmid, 50ug I-Sce1 plasmid, 50ug eGFP transfection control plasmid | kit | 14320 |
| DRT5050-2 | Detailed protocols with 250ug of cNHEJ plasmid, 250ug I-Sce1 plasmid, 50ug eGFP transfection control plasmid | kit | 54320 |
| DRT5050-3 | Detailed protocols with 500ug of cNHEJ plasmid, 500ug I-Sce1 plasmid, 50ug eGFP transfection control plasmid | kit | 79920 |
| DRT5050-4 | Detailed protocols with 1000ug of cNHEJ plasmid, 1000ug I-Sce1 plasmid, 50ug eGFP transfection control plasmid | kit | 95920 |
| TG1050-1 | Topoisomerase Type IIa Nuclear Extraction/Assay Kit | 100assays | 6560 |
| TG1001-1 | Topoisomerase II Assay Kit (20ug kDNA) | 100assays | 5120 |
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